PK/PD - General Concepts and Advanced Material

Pre-Conference Workshop
on Tuesday, September 07, 2004, and
on Wednesday, September 08, 2004
9 AM to 5 PM



IB Bondareva (Moscow, Russia)
GL Drusano (Albany, New York, USA)
NH Holford (Auckland, New Zealand)
U Jaehde (Bonn, Germany)
RW Jelliffe (Los Angeles, California, USA)
C Kloft (Berlin, Germany)
RE Port (Heidelberg, Germany)
AA Vinks (Cincinnati, Ohio, USA)
M Weiss (Halle, Germany)

Workshop Program

Beginner - Intermediate Level
Intermediate - Advanced - Expert Level

This workshop will not focus on antiinfectives like the "Pre-Conference-ISAP-Workshop" on Wednesday, September 08, 2004. The Tuesday / Wednesday workshop "PK/PD - General Concepts" deals with general principles applicable to antiinfectives and non-antiinfectives. Topics include population modeling with parametric and non-parametric methods, Monte Carlo simulations, dose individualization and optimization, optimal sampling theory, influence of demographic factors on pharmacokinetics, pharmacometrics, and related topics.

Please note our new parallel session on "Applications in Anticancer Drug Therapy" on Wednesday afternoon.

Participants will be grouped into a "beginner - intermediate" and an "advanced-expert" group. There will be a special introduction on Monday, September 06, 2004, and on Tuesday morning to learn the basic background in anatomy, physiology, biochemistry and pharmacy for chemists, physicists, computer scientists and other researchers.

This workshop also covers intermediate and advanced topics in pharmacokinetics, pharmacodynamics and the drug development process. The advanced topics in the workshops are intended for course participants who work in these fields or around and may improve their skills by listening to and discussing with the lecturers, who are world experts in their fields. Thus, we would very much like to invite also experienced scientists to participate in this workshop. Of course, advanced questions may also be raised during the "Meet-the-Tutor-Professor" sessions (see Young Investigator program for details). There is no age limit for participation in the workshop and "Meet-the-Tutor-Professor" sessions.

This workshop will have different groups that will be formed, according to knowledge, skills and exercises, before the workshop. This course also aims at allowing "non-mathematics-folks" to understand the basic principles of pharmacokinetics and pharmacodynamics.


Introductory couse for real beginners.
For persons from all educational backgrounds (also chemistry, physics and computer science).
Basic principles and methods of calculation of PK will be explained. No mathematical or microbiological background necessary. PK will be explained on a physiological basis, easy to understand if you know that the body has organs.


Pragmatic user of PK terms like clearance, t1/2 and AUC. Hardly any mathematical requirements. Course level for persons who have been in touch with pharmacokinetics / pharmacodynamic and who would like to improve their skills.


Should (must not) publish in the area, knows all the typically applied principles in PK / PD and microbiology. Is not expected to have highly sophisticated skills in PK / PD analysis, like use of population models or Monte Carlo Simulation.

(together with advanced)

As the lecturers of this course are leading world experts on their fields, this course is also highly attractive for experts in PK / PD. You will have the possibility to discuss your own problems with the lecturers who will highly appreciate your questions before, during and after the course hours. Please feel free to contact us, if we may prepare a special problem for discussion. Just write an email to and in copy to



There is a special offer "Week of Ehrlich Excellence" (see Conference Registration Form for further details) which includes all workshops.

For Participants with limited financial support:
Students with written certification by head of department may get a price reduction. Participants from Eastern Europe and Third World Countries may also get a price reduction. Please send an e-mail to Professor F. Sörgel for reduced fee requests until May 01, 2004 (e-mail: